stable micelle, pharmaceutical or cosmetic composition comprising stable micelle, method of preparing a stable micelle, method of treating a p-glycoprotein (p-gp) dependent multidrug resistant (mdr) drug for cancer, sustainable release method one or more charge molecules and stable micelle utilization
OMATHANU P. PERUMAL,RANJITH KUMAR AVERINENI,SATHEESH PODARALLA
申请号：
BR112013021732
公开号：
BR112013021732A2
申请日:
2012.02.24
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. The invention also encompasses a prolamine protein conjugated to a polymer, such as a polyethylene glycol (PEG) chain, which conjugates can be used to prepare micelle assemblies. The invention further encompasses methods of encapsulating molecules using the conjugates of the invention. The micelle assemblies can be used for a variety of applications, such as treating cancer, targeting tumors, reducing the toxicity of a drug in vivo, increasing the efficacy of an encapsulated agent in vivo, protecting an encapsulated agent against degradation, and enhancing the water solubility of a drug or other agent.
