CD1D-RESTRICTED NKT CELLS AS A PLATFORM FOR OFF-THE-SHELF CANCER IMMUNOTHERAPY

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专利权人:

Baylor College of Medicine

发明人:

Leonid S. Metelitsa,Jingling Jin,Bin Liu

申请号：

US16637986

公开号：

US20200216810A1

申请日:

2018.08.10

申请国别(地区):

US

年份:

2020

代理人:

摘要：

An isolated human NKT cell or a plurality of cells thereof, having reduced or no detectable expression of endogenous beta-2-microglobulin (B2M)； endogenous MHC class II-associated invariant chain (Ii)； or both. Methods to generate the cell or cells, and methods of treatment using the cell or cells are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/