Alessandro Accetta,Fabio Rancati,Anna Maria Capelli,David Edward Clark,Patrizia Tisselli,Christine Edwards,Gurdip Bhalay
申请号：
US15850720
公开号：
US20180170939A1
申请日:
2017.12.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Bicyclic dihydropyrimidine-carboxamide compounds of formula I described herein inhibit Rho Kinase and may be useful in the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and pulmonary arterial hypertension (PAH).
