Denis Leclerc,Nathalie Majeau,Constantino III Roberto Lopez-Macias,Alain Lamarre
申请号：
US11556678
公开号：
US08101189B2
申请日:
2006.11.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An immunopotentiating composition comprising a papaya mosaic virus (PapMV), or a virus-like particle (VLP) derived from PapMV coat protein, which is capable of functioning as an adjuvant and thus potentiating an immune response in an animal is provided. The immunopotentiating composition can further comprise an immunogen, which can be fused or otherwise linked to the VLP, or not linked to the VLP. The immunopotentiating composition is capable of potentiating a humoral and/or a cellular response in the animal and is suitable for use as an adjuvant or vaccine. Methods of potentiating an immune response in an animal comprising administering to the animal an immunopotentiating composition are also provided have application in both human and veterinary medicine.
