the present invention 2-phenyl -4-cyclopropyl-pyrimidine derivatives and thrombosis in humans and other mammals (thrombosis) and including, platelet aggregation (platelet aggregation) and associated peripheral vascular (peripheral vascular ), built vessels (visceral vascular), liver blood vessels (hepatic vascular), renal vessels (renal vascular), cardiovascular (cardiovascular) and cerebrovascular (cerebrovascular) disease or disorder of the treatment and / or prophylaxis in the P2Y 12 relates to their use as receptor antagonists (receptor antagonist).본 발명은 2-페닐-4-시클로프로필-피리미딘 유도체 및 인간과 다른 포유동물에서 혈전증(thrombosis)을 비롯한, 혈소판 응집(platelet aggregation)과 연관된 말초 혈관(peripheral vascular), 내장 혈관(visceral vascular), 간혈관(hepatic vascular), 신혈관(renal vascular), 심혈관(cardiovascular)과 뇌혈관(cerebrovascular) 질환이나 장애의 치료 및/또는 예방에서 P2Y12 수용체 길항물질(receptor antagonist)로서 이들의 용도에 관계한다.
