Adenosine receptor agonists and antagonists to modulate T cell responses

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专利权人:

Jonathan D Powell

发明人:

Jonathan D Powell,Charles George Drake,Paul Zarek

申请号：

US12676741

公开号：

US09585957B2

申请日:

2008.09.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Described are uses of A2a adenosine receptor antagonists and agonists to provide long term modulation of immune responses. A2a receptor antagonists in particular are provided to enhance immune responses by reducing T-cell mediated tolerance to antigenic stimuli and agonists are provided to enhance effectiveness of immunosuppressive agents. The application provides methods of treatment and prevention based on the long term effects of the compounds on T cell responses.

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中国工程科技知识中心

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http://www.ckcest.cn/home/