David E. FISHER,Jennifer A. LO,Dieter MANSTEIN,Masayoshi KAWAKUBO
申请号:
US15773919
公开号:
US20180311505A1
申请日:
2016.11.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are methods that can be used to produce a local immune response in cancer tissue and/or enhance effectiveness of cancer treatment in a subject through application of one or more combinations of: an ablative fractional laser procedure, a checkpoint inhibitor, and an endosomal TLR agonist (e.g., a TLR3, TLR7, TLR8 or TLR9 agonist).