The present invention relates to a flavonoid composition, comprising: quercetin, the quercetin selected from the group consisting of aglycone quercetin, quercetin glycoside, and isoquercetin, the quercetin present in an amount of about 7.9% to about 16% (w/w); green tea extract; blueberry anthocyanidins; caffeine; and n3-polyunsaturated fatty acids (N3-PUFA), wherein the flavonoid composition is formulated as a capsule, a chewable tablet, or a gummy. The flavonoid compositions are formulated to improve the bioavailability of quercetin. The composition is suitable for use in methods for improving athletic performance, improving cardiovascular health, and aiding in immune response and methods of improving athletic performance, improving bone health, preventing fatigue, reducing recovery time after exercise, countering oxidative stress, and/or boosting energy.