Arthur B. Raitano,Karen Jane Meyrick Morrison,Wangmao Ge,Pia M. Challita-Eid,Aya Jakobovits
申请号：
US12694209
公开号：
US08124741B2
申请日:
2010.01.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A novel gene 024P4C12 (also designated 24P4C12) and its encoded protein, and variants thereof, are described wherein 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 24P4C12 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 24P4C12 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response antibodies or T cells reactive with 24P4C12 can be used in active or passive immunization.
