MODULATION THERAPEUTICS;H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.;UNIVERSITY OF SOUTH FLORIDA
发明人:
MARK MCLAUGHLIN,PRIYESH JAIN
申请号：
US14574776
公开号：
US20150105328A1
申请日:
2014.12.18
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention concerns peptoid-peptide hybrids that may act as protein interaction inhibitors (PPIIs). Another aspect of the invention concerns a method for treating a disorder (e.g., an oncologic disorder) in a human or animal subject, comprising administering an effective amount of a peptoid-peptide hybrid (a peptoid body) of the invention, or a composition comprising a peptoid-peptide hybrid, to the subject in need thereof. Another aspect of the subject invention concerns a method for killing or inhibiting the growth of cells (e.g., cancer cells or malaria-infected cells), comprising contacting a cancer cell in vitro or in vivo with an effective amount of a peptoid-peptide hybrid, or a composition comprising the peptoid-peptide hybrid. Another aspect of the invention concerns a method for producing a peptoid-peptide hybrid.
