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PROTEIN FUSION CONSTRUCTS POSSESSING THROMBOLYTIC AND ANTICOAGULANT PROPERTIES
专利权人:
发明人:
申请号:
EP11814173.8
公开号:
EP2600891A2
申请日:
2011.08.05
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention discloses novel hybrid proteins that have both plasminogen activator and anti-thrombotic properties, including clot specific action, that renders these as highly advantageous for the treatment of circulatory disorders involving fibrin clot formation due to underlying tissue damage in the blood vessels leading to myocardial infarction, strokes etc. Also disclosed are new proteins, and methods of obtaining the same, that help to dissolve blood clots by activating plasminogen in a plasmin or thrombin dependent manner and also inhibit both the activity and generation of thrombin through the intrinsic pathway of blood coagulation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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