Apparatuses and methods to generate high frequency shock waves in a controlled manner. The generated shock waves can be delivered to certain cellular structures of a patient for use in medical and/or aesthetic therapeutic applications. The shock waves can be configured to impose sufficient mechanical stress to the targeted cells of the tissue to rupture the targeted cells. Embodiments of the apparatuses and methods of the present invention provide targeted rupturing of specific cells without damaging side effects such as cavitation or thermal degradation of surrounding non-targeted cells.以一控制方式來產生高頻震波之裝置及方法。能夠將所產生之震波傳送至患者之某些細胞結構,以具有醫療以及/或者美療之應用。能夠配置震波以將足夠之機械應力施加至組織之標靶細胞,以使標靶細胞破裂。本發明之裝置及方法實施例提供了特定細胞之靶向性破裂,而不會引起周圍非標靶細胞之傷害性副作用,如穴蝕或熱降解。