JOHN J. BARRY,ANDREAS GOESSL,HEINZ GULLE,MONIKA MANGOLD,MELITTA BILBAN
申请号:
HRP20120092
公开号:
HRP20120092T1
申请日:
2012.01.26
申请国别(地区):
HR
年份:
2012
代理人:
摘要:
That the present invention has instructed is micropore, injectable, gentle elastic, can be resorbent fully, based on fibrinous compositions, it is as soft tissue inner chamber and void filler.The physical features that compositions table of the present invention reveals such as engineering properties, usually what be observed aspect elastomer and the mechanical stability, is better than independent fibrin.The multiple character of the present composition can be comprised in the type of the particle in the void filler compositions and the type and the content of content and plasticizer carries out meticulous adjusting and change by adjusting.Injektabilna smjesa koja se koristi za lumen mekog tkiva ili punilo za praznine u mekom tkivu, naznačena time, da ta smjesa sadrži: komponentu (a) koja sadrži fibrinogen, komponentu (b) koja sadrži trombin ili sredstvo koje potiče geliranje ili sredstvom za zgrušavanje za komponentu (a), komponentu (c) koja Sadrži najmanje jedan plastifikator i komponentu (d) koja sadrži mikročestice s prosječnim promjerom čestice između 0,01 - 200 pm, pri čemu se količina mikročestica kreće u rasponu od 10 do 45 % t/t ukupne smjese. Patent sadrži još 17 patentnih zahtjeva.