A dental floss and post-floss cleaning system including a plurality of floss-and-post-floss-cleaning assemblies and a dental floss and wiping implement dispenser. The dispenser may have a dispenser cavity and may be configured to hold, within the dispenser cavity, and dispense, out of the dispenser cavity, the plurality of floss-and-post-floss-cleaning assemblies. Each of the plurality of floss-and-post-floss-cleaning assemblies may be configured as a single-use assembly and each may include a single-use wiping implement made of a flexible and absorbent material suitable for wiping post-floss food particles and saliva and a corresponding pre-cut dental floss strand having a predetermined length and being removeably affixed to the single-use wiping implement.