COMBINED APPLICATION OF GDF TRAPS AND ACTIVATORS OF ERYTHROPOIETHIN RECEPTORS TO ENHANCE THE CONTENT OF ERYTHROCYTES

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专利权人:

发明人:

申请号：

RU2017145301

公开号：

RU2017145301A3

申请日:

申请国别(地区):

RU

年份:

2019

代理人:

摘要：

Compositions for increasing red blood cell levels or treatment of anemia comprising erythropoietin receptor activators and a variant Activin RIIB (ActRIIB) polypeptide having a leucine residue replaced by a acidic amino acid residue, where the variant ActRIIB polypeptide has a reduced affinity for activin B and may be called a GDF trap. Methods for the use of these compositions.

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