These include the components of these compounds, and the use of these compounds and components to control the genetic response of bromine controlled intermediates to acetyllysine protein regions, such as rectal tissue. These ingredients and methods help to treat diseases caused by abnormal cell signals, such as inflammation, cancer and emerging diseases. Claim 1: a compound or a pharmaceutically acceptable salt of such a compound, the structure of which is in the form of formula (1), including hydrogen, tar, arilo, aralquilo, cyclopentadiene, cyclopentadienyl, isocyclopropylene,e. Isocyclopropyl, heteromorphic or heteromorphic cyclopropyl； x8310es C-H, C-F, C-Cl, C-Br or N； r83099 is hydrogen, halogen-cn, tar, cyclopropyl or propoxy； r8310s is hydrogen, halogen-cn, tar, cyclopropyl, cyclopropyl, cyclopropylenyl, cyclopropene-o2 or n (R2) 8322；A is a formula compound (2)；R¹³ is -Y-Z； Y is selected from a bond, -CH₂- or -CH (C₁₋₄-alkyl) -；Z from - so83222； R2,-N (R) SO R-SO N (R)-N (R) SO N (R)-CON (R)-N (R) CO R-N (R) CON (R)-N (R) COR-COR²¹,-OC (O) N (R)-OSO N (R)-OSO₂R²¹,-N (R) SO RN (R2) 832222； o-cn； X2 is n or c-r1；R2 is hydrogen, halogen-cn, tar, cyclopentyl or alcoxi； X 83088n or c-r830808；Where r83088 is hydrogen, halogen, CN, tar, cyclo or alcoxi； X is a link, O -,- yes.-N (R) --CH₂-,-CF (H)..CF - o -CH (alquilo C) -R8311811 is rent h or c8332131； 832626；R¹ is alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl or heteroarylalkyl； each R²¹ is independently selected from alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl or heteroarylalkyl； each R²² is independently selected from hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl or heteroarylalkyl； and with the proviso that the compound of formula (1) is not N- [2- (2,4-difluorophenoxy) -6- (1,5-dimethyl-6-oxopyridin-3-yl) pyrimidin-4-yl ] ethanesulfinamide.Composicione
