The method of bright Ti Gong System Prepare formula (A) compound represented of this Hair,The method comprises the following steps: (a) in the case where adding Hot,The small what 1 of Hua He Wu With phase Right what formula (B) compound represented As shown in Will formula (B) rubs the Right toluenesulfonic acid of Seoul When amount or Right toluenesulfonic acid monohydrate mixes in molten Elixirs； (b) under Leng They,Right toluenesulfonic acid or Right toluenesulfonic acid monohydrate into the mixed solution outside Jia Ru Amount,The additional amount of Right toluenesulfonic acid or Right toluenesulfonic acid monohydrate outside Qi Zhong Suo Shu Amount wants the Total of Right toluenesulfonic acid or Right toluenesulfonic acid monohydrate in Qi With process (a) of Shi get Seoul When amount phase Right what process (a) Chinese style (B) the compound represented As 1 that rubs to rub Seoul When amount or more； (c) Hun is then made to close Rong Ye Knot crystalline substance to obtain formula (A) compound represented.本發明提供了製備式(A)所示的化合物的方法，該方法包括如下工序：(a)在加熱下，將式(B)所示的化合物與相對於式(B)所示的化合物為小於1摩爾當量的對甲苯磺酸或對甲苯磺酸一水合物在溶劑中混合；(b)在冷卻下，向所述混合溶液中加入額外的對甲苯磺酸或對甲苯磺酸一水合物，其中所述額外的對甲苯磺酸或對甲苯磺酸一水合物的加入量要使得其與工序(a)中的對甲苯磺酸或對甲苯磺酸一水合物的總摩爾當量相對於工序(a)中式(B)所示的化合物為1摩爾當量或更多；和(c)接着使所述混合溶液結晶以得到式(A)所示的化合物。
