MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;THE JOHNS HOPKINS UNIVERSITY;BUCK INSTITUTE FOR RESEARCH ON AGING;UNITY BIOTECHNOLOGY INC.
发明人:
申请号:
IL24695416
公开号:
IL246954D0
申请日:
2016.07.26
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.