Spojine, ki modulirajo androgeni receptor

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专利权人:

ORION CORPORATION

发明人:

WOHLFAHRT GERD,TORMAKANGAS OLLI,SALO HARRI,HOGLUND IISA,KARJALAINEN ARJA,KNUUTTILA PIA,HOLM PATRIK,RASKU SIRPA,VESALAINEN ANNIINA,WOHLFAHRT Gerd,TORMAKANGAS Olli,SALO Harri,HOGLUND Iisa,KARJALAINEN Arja,KNUUTTILA Pia,HOLM Patrik,RA

申请号：

SI201030739

公开号：

SI2493858T1

申请日:

2010.10.27

申请国别(地区):

SI

年份:

2014

代理人:

摘要：

Compounds of formula (I) wherein R 1 to R 16 , A. B and E are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

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