Improved fluoresced imaging (FI) and other sensor data imaging processes, devices, and systems are provided to enhance display of different secondary types of images and reflected light images together. Reflected light images are converted to a larger color space in a manner that preserves the color information of the reflected light image. FI or secondary images are transformed to a color range within the larger color space, but outside the color area of the reflected light images, allowing the FI or secondary images to be combined with them in a manner with improved distinguishability of color. Hardware designs are provide to enable real-time processing of image streams from medical scopes. The combined images are encoded for an electronic display capable of displaying the larger color space.