CEACAM5 PEPTIDES FOR CROHN'S DISEASE

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专利权人:

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

发明人:

Giulia RODA,Lloyd MAYER

申请号：

US15308595

公开号：

US20170189484A1

申请日:

2015.05.01

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to small peptides, derived from the N-terminal domain of CEACAM5 (carcinoembryonic antigen family member 5), with the ability to stimulate the suppressive activity of CD8+ T cells in Crohn's disease. Pharmaceutical formulations, methods to treat patients with Crohn's disease, and methods to identify candidate peptides for treatment of Crohn's disease patients, are also disclosed.

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