Aqueous Liquid formulations of rupatadine fumarate free Cyclodextrins are useful for the treatment of allergic rhinitis and urticaria. These formulations comprising rupatadine fumarate, one or more cosolvents and one or more Regulators where the composition has a pH between pH 4 and pH 6.5.Claim 1: a free Cyclodextrins aqueous Liquid Pharmaceutical composition characterized in that it comprises: rupatadine fumarate, one or more co Solvent, one or more ph adjusting agents, wherein the composition has a pH between 4 and 6.5.Claim 3: a Pharmaceutical composition according to any of the preceding Claims, wherein the total amount of co Solvent (S) is from 5 to 50% of the formulation.A Pharmaceutical composition according to claim 5: any of the preceding Claims, wherein the composition comprises one or more co Solvent selected from the group consisting of isopropanol, ethanol, Propylene Glycol, Glycerin, Macrogol 300, macrogol 400, dimetilace TAMIDA and pyrrolidone.Pharmaceutical composition according to claim 7: a claim 5 wherein the composition comprises one or more selected from the group consisting of cosolvent ethanol, Propylene Glycol, Macrogol 300 and Macrogol 400.A Pharmaceutical composition according to claim 8: claim 7 wherein the co Solvent selected from the group consisting of propylene glycol and Macrogol 400A Pharmaceutical composition according to claim 11: claim 10, wherein the one or more ph adjusting agents selected from the group consisting of tampons Na2HPO4 / Citric Acid, phosphate, Citrate buffer, acetic acid / acetate and ammonium acetate / Edeta sadistic To sodium.A Pharmaceutical composition according to claim 12: 11 Claims, characterized in that the composition comprises a buffer selected from the group consisting of Na2HPO4 / Na2HPO4 / Citric Acid and KH2PO4. 14 a Pharmaceutical composition according to claim: the claim 13 wherein the composition comprises a pH Regulator which is NaOH.21: a Pharmaceutical composition according to claim any
