DAOUST MARC ANDRE,COUTURE MANON,VEZINA LOUIS PHILIPPE
申请号:
IN3077CHN2014
公开号:
IN3077CHN2014A
申请日:
2014.04.24
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
A method of producing a virus like particle (VLP) in a plant is provided. The method comprises introducing a first nucleic acid and a second nucleic acid into the plant or portion of the plant. The first nucleic acid comprises a first regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a structural virus protein. The second nucleic acid comprises a second regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a channel protein for example but not limited to a proton channel protein. The plant or portion of the plant is incubated under conditions that permit the expression of the nucleic acids thereby producing the VLP.