ESPLING, ERIK STEPHEN,BAUM, PETER ROBERT,THOMPSON, PETER ARMSTRONG
申请号：
AU2013201195
公开号：
AU2013201195A1
申请日:
2013.03.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
A composition comprising recombinant immunoglycoproteins, wherein the recombinant immunoglycoprotein molecules each comprise a binding domain that specifically binds to CD37 and have at least a 5-fold increase in antibody-dependent cellular cytotoxicity (ADCC) as compared to control immunoglycoproteins of the same encoded amino acid sequence produced in Chinese Hamster Ovary (CHO) cells, and wherein at least 60% of the recombinant immunoglycoprotein molecules are non-fucosylated.
