Joseph Ventura,Shannon Wadman,Joram Slager,Joseph Schmidt McGonigle,Robert W. Hergenrother
申请号：
US14072520
公开号：
US09555119B2
申请日:
2013.11.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.
