N-{[2- (Piperidin-1-yl) phenyl] (phenyl) methyl} -2- (3-oxo-3,4-dihydro-2H-1 as a ROR gamma modulator for treating autoimmune diseases , 4-benzoxazin-7-yl) acetamide derivatives and related compounds
The present invention relates to N- as ROR gamma modulator for treating autoimmune diseases, autoimmune related diseases, inflammatory diseases, metabolic diseases such as fibrotic diseases such as arthritis, asthma or cholestatic diseases. {[2- (Piperidin-1-yl) phenyl] (phenyl) methyl} -2- (3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl) acetamide derivatives and related compounds I will provide a.本発明は、例えば、自己免疫疾患、自己免疫関連疾患、炎症性疾患、代謝性疾患、例えば関節炎、喘息のような線維性疾患又は胆汁鬱滞性疾患を治療するためのRORガンマモジュレーターとしてのN-{[2-(ピペリジン-1-イル)フェニル](フェニル)メチル}-2-(3-オキソ-3,4-ジヒドロ-2H-1,4-ベンゾオキサジン-7-イル)アセトアミド誘導体及び関連化合物を提供する。