A pharmaceutical composition comprising: a. an effective amount of a compound of Formula B: or a pharmaceutically acceptable salt thereof； b. a second therapeutic agent selected from insulin or insulin analogues, glucagon-like-peptide-1 (GLP-1) receptor agonists, sulfonylurea agents, biguanide agents, alpha-glucosidase inhibitors, PPAR agonists, meglitinide agents, dipeptidyl-peptidase (DPP) IV inhibitors, phosphodiesterase inhibitors, amylin agonists, CoEnzyme A inhibitors, and antiobesity agents； and c. a pharmaceutically acceptable car.
