CASTAIGNE JEAN PAUL,DEMEULE MICHEL,BOIVIN DOMINIQUE,LAWRENCE BETTY,CHE CHRISTIAN
申请号:
IN4609/CHENP/2011
公开号:
IN2011CN04609A
申请日:
2011.06.28
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a leptin, a leptin analog, or OB receptor agonist. The compounds of the invention can be used to treat any disease in which increased amounts of leptin are desired, such as metabolic diseases including obesity and diabetes.