Disclosed are ophthalmic drug-delivery devices (40), comprising a body (42)having a proximal end (45) and a distal end (43), wherein the body includes a styreneelastomer matrix and a drug in contact with the matrix. Also disclosed are methodsof treating or preventing an eye disease in a subject, that involve contactingan eye. of the subject with an ophthalmic drug delivery device comprising a bodyhaving a proximal end and a distal end, wherein the body comprises a styrene elastomermatrix and a drug in contact with the matrix, wherein release of the drug from thedevice occurs over time following contacting of the device with the eye of thesubject.