Provided is an inflatable insulation box relating to the technical field of cold insulation equipment for cold chain transportation, comprising a box body and a box lid, wherein the box body has an opening and the box lid is configured to close the opening of the box body； the box body and the box lid include fabrics on outer layers and airbags on inner layers, respectively； an air valve is provided on the box body and/or the box lid to inflate or deflate the airbags； reflective fabrics may also be used on inner surfaces of the box body and the box lid to improve thermal insulation performance. This inflatable insulation box has good thermal insulation effect, and can be conveniently inflated and deflated and conveniently folded up, reducing occupied space.
