ТАН Пэн Чо (CN),ЛУ Хэцзюнь (CN),ЧЭЙ Хунбо (CN),ЧЭНЬ Ицянь (CN)
申请号：
RU2011153934/04
公开号：
RU2011153934A
申请日:
2010.05.28
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. Pharmaceutically acceptable salts of a compound of formula (I) wherein Het is selected from the group consisting of phenyl, furyl, and thienyl； R, R, R, and R are each independently selected from the group consisting of hydrogen and alkyl； n is 0, 1, or 2； salts are base addition salts. 2. The pharmaceutically acceptable salts of claim 1, wherein they are salts of a compound of formula (IA) wherein Het is selected from the group consisting of phenyl, furyl and thienyl； R, R, R, and R are each independently selected from the group consisting of hydrogen and alkyl； M is selected from the group consisting of a metal ion, an ammonium ion and a basic amino acid； m is 1 or 2； n is 0, 1 or 2； salts are base addition salts. 3. The pharmaceutically acceptable salts of claim 1 or 2, wherein the salts are selected from the group consisting of sodium salt, lithium salt, potassium salt, calcium salt, magnesium salt, arginine salt, lysine salt, methanamine salt, dimethylamine salt, trimethylamine salt, ethylamine salt , diethylamine salts, triethylamine salts, ethanolamine salts, piperazine salts, dibenzylethylenediamine salts, meglumine salts, trometamine salts, quaternary tetramethylammonium salts, quaternary tetraethylammonium salts and choline salts, preferably diethylamine salts, ethanolamine salts, choline salts, pip salts Razin, meglumine salt and tromethamine salt, more preferably a salt of ethanolamine, choline salt, meglumine salt and tromethamine salt, and most preferably salts etanolamina.4. The pharmaceutically acceptable salts of claim 1, wherein the salts are selected from the group consisting of: 5. A method of obtaining a pharmaceutically acceptable salt according to any one of claims 1 to 4, comprising the following steps: (a) dissolving or suspending a compound of formula (I) in organic1. Фармацевтически приемлемые соли соединения формулы (I)где Het выбран из группы, состоящей из фенила, фурила и тиенила；R, R, Rи Rкаждый независимо выбран из группы, состояще
