The present invention discloses a traditional chinese drug consisting of Danshen extracts and Sanqi extracts, the pharmaceutical composition comprising the above traditional chinese drug as active component and the use thereof. The traditional chinese drug consists of Danshen extracts and Sanqi extracts by weight ratio of (2-6):(0.5-2). The invention further discloses the effect of the traditional chinese drug and the pharmaceutical composition comprising the above traditional chinese drug as active component for treating cardiac microcirculation disturbance and myocardial damage induced by ischemia reperfusion.