AMY C. HART,ASHOK VINAYAK PURANDARE,ASHVINIKUMAR V. GAVAI,BIN CHEN,BRIAN E. FINK,CHRISTINE M. TARBY,GUIFEN ZHANG,HAROLD MASTALERZ,HONGHE WAN,JENNIFER INGHRIM,JOHN S. TOKARSKI,KURT ZIMMERMANN,LIBING CH
申请号：
BR112015000704
公开号：
BR112015000704A2
申请日:
2013.07.12
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Patent Summary: "Imidazotriazinecarbonitriles useful as kinase inhibitors". The invention provides compounds of formula (I) (I) and pharmaceutically acceptable salts thereof. Imidazotriazines of formula (I) inhibit protein kinase activity, thereby rendering them useful as anticancer agents.resumo patente de invenção: "imidazotriazinacarbonitrilas úteis como inibidores de quinase". a invenção proporciona compostos de fórmula (i) (i) e sais farmaceuticamente aceitáveis dos mesmos. as imidazotriazinas de fórmula (i) inibem atividade de quinase de proteína, deste modo, tornando as úteis como agentes anticâncer.
