ANTICORPOS INIBIDORES QUE SE LIGAM AO COMPLEXO ATIVADOR PLASMINOGÉNICO DO TIPO UROQUINASA (UPA) E SEU RECEPTOR (UPAR)

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专利权人:

TACTIC PHARMA; LLC

发明人:

GRAHAM C. PARRY,ANDREW P. MAZAR

申请号：

PT05754219

公开号：

PT1765397E

申请日:

2005.05.25

申请国别(地区):

PT

年份:

2013

代理人:

摘要：

Antibodies or other ligands specific for the binary uPA-uPAR complexes, for ternary complexes comprising uPA-uPAR and for complexes of uPAR and proteins other than uPA such as integrins inhibit the interaction of uPA and uPAR with additional molecules with which the complexed interact. Such antibodies or other ligands are used in diagnostic and therapeutic methods, particularly against cancer.

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