Johan Andersson,Helena Gybäck,Anh Johansson,Christian Erik Linde,Jonas Malmström,Gunnar Nordvall,Tatjana Weigelt,Gitte Terp
申请号：
US12824567
公开号：
US08367676B2
申请日:
2010.06.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to compounds of formula (I),whereinR1 is heteroaryl or heterocyclyl, optionally substitutedR2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substitutedR3 is hydrogen or C1-4alkyl, orR2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substitutedR4 is hydrogen, halogen, methyl or methoxyto pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders.The present invention further relates to new intermediates useful in the preparation thereof.
