Multi-luminal endoscopic systems for sterilely delivering deployable devices or obtaining bodily tissues. The system comprise an outer catheter comprising a wall that encloses an outer lumen an inner catheter movably disposed within the outer lumen and having an inner lumen a balloon-tipped catheter movably disposed within the inner lumen and having a distal end and a proximal end, wherein the distal end of the balloon-tipped catheter comprises a balloon tip that can be expanded to contact the wall of the outer catheter to provide a seal to prevent bodily fluids from entering the outer lumen and a push catheter having a lumen and is located within the outer lumen. The delivery systems can comprise concentric catheters. Systems used for tissue collecting can comprise catheters with different common center.