경북대학교 산학협력단;KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
조영제,이은호,CHO YOUNG JE,LEE EUN HO
申请号：
KR1020180127806
公开号：
KR1020200046524A
申请日:
2018.10.24
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
The present invention relates to a composition for improving antioxidant, anti-inflammatory, anti-diabetic, or wrinkles containing a topaz apple peel extract as an active ingredient, Hwangok apple peel extract according to the present invention is DPPH radical, ABTS It has an antioxidant effect by inhibiting radicals and TBARs and increasing PF, and suppresses an inflammatory reaction by inhibiting hyaluronidase activity. In addition, by inhibiting elastase activity, the elastin molecule form is maintained, collagenase activity is inhibited, and wrinkle-improving effect is exhibited, and α-amylase and α-glucosidase enzyme activity is inhibited, thereby preventing diabetes. Therefore, it is expected that the topaz apple peel extract according to the present invention may be useful as an antioxidant, anti-inflammatory, anti-diabetic, or wrinkle-improving pharmaceutical composition, food composition, or cosmetic composition.본 발명은 황옥 사과 껍질추출물을 유효성분으로 포함하는 항산화, 항염증, 항당뇨, 또는 주름개선용 조성물에 관한 것으로, 본 발명에 따른 신육성 품종인 황옥(Hwangok) 사과 껍질추출물은 DPPH radical, ABTS radical, 및 TBARs를 저해하고 PF를 증가시킴으로써 항산화 효과를 가지며, hyaluronidase 활성을 저해함으로써 염증반응을 억제시키는 효과를 나타낸다. 또한, elastase 활성을 저해함으로써 elastin 분자 형태를 유지시키고, collagenase 활성을 저해함으로써 주름개선 효과를 나타내며, α-amylase 및 α-glucosidase 효소활성을 저해함으로써 당뇨병 예방 효과를 나타낸다. 따라서, 본 발명에 따른 황옥 사과 껍질추출물은 항산화, 항염증, 항당뇨, 또는 주름개선용 약학적 조성물, 식품 조성물, 또는 화장료 조성물 등으로 유용하게 이용될 수 있을 것으로 기대된다.
