The present specification discloses TEMs, compositions comprising such TEMs, compositions comprising such TEMs and Clostridial toxins, methods of treating an involuntary movement disorder in an individual using such compositions, use of such TEMs in manufacturing a medicament for treating an involuntary movement disorder, use of such TEMs and Clostridial toxins in manufacturing a medicament for treating an involuntary movement disorder, use of such TEMs in treating an involuntary movement disorder, and use of such TEMs and Clostridial toxins in treating an involuntary movement disorder.Linvention concerne des modulateurs dexocytose cibles (TEM), des compositions comprenant de tels TEM, des compositions comprenant de tels TEM et des toxines clostridiales, des méthodes de traitement dun trouble à mouvements involontaires chez un individu à laide de telles compositions, lutilisation de tels TEM dans la fabrication dun médicament pour le traitement dun trouble à mouvements involontaires, lutilisation de tels TEM et de toxines clostridiales dans la fabrication dun médicament pour le traitement dun trouble à mouvements involontaires, lutilisation de tels TEM dans le traitement dun trouble à mouvements involontaires, ainsi que lutilisation de tels TEM et de toxines clostridiales dans le traitement dun trouble à mouvements involontaires.
