STEPHAN SCHILLING,HOLGER CYNIS,JENS-ULRICH RAHFELD,HANS-ULRICH DEMUTH
申请号:
BRPI0718507
公开号:
BRPI0718507A2
申请日:
2007.09.21
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
The present invention relates to novel glutaminyl-peptide cyclotransferase-like proteins (QPCTLs), which are isoenzymes of glutaminyl cyclase (QC, EC 2.3.2.5), and to isolated nucleic acids coding for these isoenzymes, all of which are useful for the discovery of new therapeutic agents, for measuring cyclase activity, and for determining the inhibitory activity of compounds against these glutaminyl cyclase isoenzymes.