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MIXED IONOPHORE ION-SELECTIVE ELECTRODE FOR THE IMPROVED DETECTION OF UREA IN BLOOD
专利权人:
Radiometer Medical ApS
发明人:
KJAER, Thomas,MICHELSEN, Lone,SOERENSEN, Paul, Ravn,JAKOBSEN, Hans, Peter, Blaabjerg
申请号:
EP20160861086
公开号:
EP3391038(A1)
申请日:
2016.12.12
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
The present application discloses improved multiple-use sensor arrays for determining the content of various species in samples of biological origin, in particular in the area of point-of-care (POC) testing for blood gases. The multiple-use sensor array is arranged in a measuring chamber, and the sensor array comprises two or more different ion-selective electrodes including a first ion-selective electrode (e.g. an ammonium-selective electrode being part of a urea sensor), wherein the first ion-selective electrode includes a membrane comprising a polymer and (a) a first ionophore (e.g. an ammonium-selective ionophore) and (b) at least one further ionophore (e.g. selected from a calcium-selective ionophore, a potassium-selective ionophore, and a sodium-selective ionophore), and wherein the first ionophore is not present in any ion-selective electrode in the sensor array other than in the first ion-selective electrode.
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