Anders Nykjær,Ole J. Bjerrum,Christian Bjerggaard Vægter,Pernille Jansen
申请号：
US13000854
公开号：
US08460657B2
申请日:
2009.06.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention relates to the use of an agent capable of binding and thus inhibit formation of a binary Vps10p-domain receptor:TrpV receptor complex, and/or formation of a further ternary Vps10p-domain receptor:TrkA:TrpV receptor complex for the preparation of a medicament for the inhibition of pain and pain signalling through said complex(es). The invention is thus beneficial in the preparation of a medicament for the treatment and/or prevention of neuropathic pain, chronic pain and acute pain. The invention furthermore relates to the identification of such agents and animal models for screening for such agents.
