"soluble mutant tnfrp75, fusion protein, DNA sequences, uses of soluble mutant tnfrp75 and fusion protein and pharmaceutical compositions"

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专利权人:

SHANGHAI FUDAN-ZHANGJIANG BIO-PHARMACEUTICAL CO.,LTD;TAIZHOU FUDAN-ZHANGJIANG PHARMACEUTICAL CO., LTD

发明人:

YANJUN LIU,FANG WU,JINSONG WU,TONG YANG,YIJUN SHEN

申请号：

BRPI0906044

公开号：

BRPI0906044A2

申请日:

2009.01.12

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

A soluble tumor necrosis factor receptor 2 (TNFRII) mutant has an amino acid substitution at position 92Glu compared with the wild TNFRII. The mutant improves the cytotoxicity capacity of neutralizing TNFalpha and lymphotoxin. The mutant and fusion protein comprising it are useful for the treatment of TNFalpha and lymphotoxin related diseases.

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中国工程科技知识中心

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