Michael EHRMANN,Jasmin NELLES,Simon POEPSEL,Katharina SEVERIN
申请号:
US15564394
公开号:
US20180133328A1
申请日:
2016.04.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention is directed to methods for delivery of HTRA polypeptides and its variants into mammalian cells without using transfection reagents. The HTRA polypeptides can be coupled to cargo molecules which are thereby transported into cells, e.g. for complementation, activation or inhibition of cellular pathways for basic and translational research as well as for therapy.