BIILMANN RONN, LARS CHRISTIAN,MALIK, IBRAHIM JOHN,STAVENHAGEN, JEFFREY B.,CHRISTENSEN, SOREN,EGEBJERG, JAN,STUMMANN, TINA,GERRITSEN, ARNOUT,VAN DEN BRINK, EDWARD,PARREN, PAUL,TRABJERG, ESBEN,RAND, KAS
申请号:
CA3069391
公开号:
CA3069391A1
申请日:
2018.07.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders such as Alzheimers disease (AD).