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COMPRIMÉ POUR LAVAGE INTESTINAL ADMINISTRABLE ORALEMENT
专利权人:
Ltd.;Zeria Pharmaceutical Co.
发明人:
申请号:
EP10811523.9
公开号:
EP2476424A1
申请日:
2010.08.27
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
To provide a peroral tablet for bowel cleansing which leaves no remains in the intestinal tract after bowel cleansing, which exhibits a dissolution property equivalent to that of conventional sodium phosphate-containing tablets including crystalline cellulose, and which is a small-size agent readily taken by a subject.The peroral tablet for bowel cleansing containing the following ingredients (A) and (B):(A) 80 to 95 mass% of sodium phosphate, and(B) (B1) 7 to 11 mass% of hydroxypropyl cellulose which has such a particle size that ≥99% of the particles thereof pass through a mesh having an opening of 350 µm and whose 2-mass% aqueous solution has a viscosity of 2.0 to 10.0 mPa·s,(B2) 5 to 13 mass% of hydroxypropyl cellulose which has such a particle size that ≥99% of the particles thereof pass through a mesh having an opening of 150 µm and whose 2-mass% aqueous solution has a viscosity of 3.0 to 5.9 mPa·s, or(B3) 7 to 11 mass% of hydroxypropyl cellulose which has such a particle size that ≥99% of the particles thereof pass through a mesh having an opening of 150 µm and whose 2-mass% aqueous solution has a viscosity of 6.0 to 4,000 mPa·s, andhaving a water-insoluble ingredient content of 5 mass% or less.
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中国工程科技知识中心
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