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Bioactive substance NK13650P3, production method and use thereof
专利权人:
日本化薬株式会社
发明人:
戸村 有宏,小田中 淳子,西元 允一
申请号:
JP2007523935
公开号:
JP5030777B2
申请日:
2006.06.26
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
A physiologically active substance NK13650P3 having the following physicochemical properties or a pharmacologically acceptable salt thereof. 1) Appearance: pale yellow powder 2) Molecular formula: C 29 H 37 N 7 O 15 3) Molecular weight: 723 4) Hydrogen nuclear magnetic resonance spectrum: spectrum measured at 600 MHz in heavy water contains the following signals: chemical shift value ´ ppm: 7.05(1H,3), 7.00(1H,d), 6.96(1H,d), 6.83(1H,s), etc. 5) Carbon nuclear magnetic resonance spectrum: spectrum measured at 150 MHz in heavy water contains the following signals: chemical shift value ´ ppm: 181.5(s), 181.4(s), 179.9(s), 179.2(s), 174.5(s), 174.3(s), 271.5(s), 165.4(s), etc. 6) Ultraviolet light spectrum: spectrum measured in aqueous solution contains the following UV absorption bands: » max (MeOH): 196.5 nm, 224.5 nm, 322.5 nm 7) Solubility: highly soluble in water but insluble in methanol, acetone, ethyl acetate, chloroform and dimethyl sulfoxide. 8) Coloration reaction: positive to phosphomolybdic acid/sulfuric acid reaction and Rydon-Smith reaction.
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