A parasitic Acari barrier fabric that impedes parasitic Acari movement, traps parasitic Acari, and/or exterminates parasitic Acari thereon or therein. The barrier fabric includes an outer face formed from open mesh construction having evenly spaced openings formed thereon that are adapted for passing parasitic Acari from outside the fabric to inside the fabric, an inner face that is breathable and configured for moisture vapor transmission from a wearer's skin therethrough but is impenetrable to parasitic Acari passed to the inside of the fabric, and an intermediate spacer that extends between and interconnects the inner face to the outer face to form the parasitic Acari barrier fabric.