Vaccines comprising MAGE antigen coupled to protein D fragment

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专利权人:

GLAXOSMITHKLINE BIOLOGICALS S.A.

发明人:

GARCON, NATHALIE,GERARD, CATHERINE MARIE, GHISLAINE,STEPHENNE, JEAN

申请号：

DK07121675

公开号：

DK1889630T3

申请日:

2001.10.16

申请国别(地区):

DK

年份:

2012

代理人:

摘要：

The present invention provides novel adjuvant formulations for use with cancer antigens. The adjuvant comprises a saponin, a immunostimulatory oligonucleotide, and a lipopolysaccharide selected from Monophosphoryl Lipid A, 3-0-Deacylated Monophosphoryl Lipid A and Diphosphoryl Lipid A. The cancer antigen is selected from HASH-1 (ASCL-1) HASH-2 (ASCL-2) and a fusion protein of MAGE and protein D.

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