A handle (17000) for use with a surgical instrument system can comprise a first handle housing portion (17010) comprising an output (17037) and a second handle housing portion (17020) comprising, one, an electric motor (17030) comprising a rotatable motor shaft and, two, an actuator (17039) for operating the electric motor. The handle further comprises an articulation joint (17015), wherein the second handle housing portion is rotatably connected to the first handle housing portion about the articulation joint, and wherein the second handle housing portion is rotatable between a first grip position and a second grip position. The handle further includes a transmission (17036) configured to transmit motion between the first motor shaft and the output. The transmission comprises a cable and a slip joint (17033) configured to adjust the length of the cable depending on the position of said second handle housing portion.