Combined use of CTLA-4 blocking agent and lymphotoxic therapy in tumor therapy

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专利权人:

The Regents of the University of California

发明人:

Allison, Patrick James,Leach, Dana R.,Krummel, Matthew, F.

申请号：

DK10180032

公开号：

DK2332561T3

申请日:

1996.12.04

申请国别(地区):

DK

年份:

2016

代理人:

摘要：

T Cell activation in response to antigen is increased by the administration of binding agents that block CTLA-4 signaling. When CTLA-4 signaling is thus blocked, the T cell response to antigen is released from inhibition. Such an enhanced response is useful for the treatment of tumors, chronic viral infections, and as an adjuvant during immunization.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/